Treatment of Depression with Phenylethylamine (PEA)

Mild as well as severe forms of depression may have a simple cause, and a simple cure. A brain hormone, phenylethlamine (PEA), promotes energy and elevates mood. A deficiency in PEA renders the person weak, tired, sluggish, and depressed. Taking PEA rapidly restores well-being. PEA is a natural, physiological treatment of depression.

Our clinical observations indicate that 60% of depressed patients have a reduction in PEA metabolism, and that PEA is effective in 60% of depressed patients. PEA relieves depression very fast, in a matter of hours or days, and produces no toxic effects, tolerance or abuse.

In other words, depression is an illness very much like diabetes. In diabetes there is a (relative) deficiency of insulin, and it is treated by administering insulin. An even closer analogy is hypothyroidism. Thyroid hormones sustain bodily energy; their deficit produces a characteristic syndrome that includes depression in the adult, and mental retardation in the child. Likewise 2-phenylethylamine (PEA) is a neurohormone that sustains psychological energy. A large group of depressions, sixty percent of them, it seems, are due to a (relative) deficit in PEA, and can be treated by giving PEA.

Fortunately, unlike insulin, PEA can be taken by mouth. However, PEA is rapidly destroyed in the body. To prevent its rapid destruction, it must be protected by the simultaneous administration of low doses of selegiline (Eldepryl), a medication used in elderly people to slow down the progress of Parkinson disease.

PEA controls depression in 60% of depressed persons--the same percentage as all major antidepressants such as Prozac--but it is less toxic.

PEA is by no means a panacea that controls all depressions, but it may deserve to be used as the first treatment to try because it acts fast, and it can be used for long periods of time without fear of harmful consequences such as weight gain, sexual inhibition, and other common side effects of antidepressant drugs. This is because PEA replacement is a physiological treatment of depression.

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Last update: October 24, 2006